In Vitro Murine Spermatogenesis in an Organ Culture System1
نویسندگان
چکیده
منابع مشابه
In vitro mouse spermatogenesis with an organ culture method in chemically defined medium
We previously reported the successful induction and completion of mouse spermatogenesis by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential medium (α-MEM), supplemented with Knockout serum replacement (KSR) or AlbuMAX, neither of which were defined chemically. In this study, we formulated a chemically defined medium (CDM) that can induce mouse spermatogenes...
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The adult testis is the male reproductive organ that produces sex hormones for sexual behaviours and sperm in a well-controlled process called spermatogenesis. Spermatogenesis involves self-renewal and differentiation of the male germ stem cells spermatogonia, culminating in the production of sperm for germline transmission. Retinoic acid (RA) is essential for fate decision and meiosis entry of...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2010
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.110.083899